Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | HUMANCYC_SUPERPATHWAY OF HISTIDINE, PURINE, AND PYRIMIDINE BIOSYNTHESIS |
| Enrichment Score (ES) | 0.819875 |
| Normalized Enrichment Score (NES) | 1.6678768 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0070160893 |
| FWER p-Value | 0.135 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ATIC | 14231 3968 | 53 | 9.237 | 0.0649 | Yes | ||
| 2 | NME2 | 9468 | 56 | 9.099 | 0.1315 | Yes | ||
| 3 | IMPDH2 | 10730 | 85 | 8.592 | 0.1930 | Yes | ||
| 4 | NME1 | 9467 | 97 | 8.436 | 0.2542 | Yes | ||
| 5 | CAD | 16886 | 121 | 7.983 | 0.3115 | Yes | ||
| 6 | PPAT | 6081 | 124 | 7.966 | 0.3698 | Yes | ||
| 7 | NME4 | 23065 1577 | 152 | 7.602 | 0.4241 | Yes | ||
| 8 | GART | 22543 1754 | 159 | 7.447 | 0.4784 | Yes | ||
| 9 | ADSL | 4358 | 162 | 7.442 | 0.5329 | Yes | ||
| 10 | NME6 | 3139 19297 | 233 | 6.695 | 0.5782 | Yes | ||
| 11 | PAICS | 16820 | 249 | 6.605 | 0.6258 | Yes | ||
| 12 | GUK1 | 20432 | 253 | 6.591 | 0.6740 | Yes | ||
| 13 | RRM1 | 18163 | 384 | 5.624 | 0.7082 | Yes | ||
| 14 | GMPS | 15578 | 404 | 5.492 | 0.7475 | Yes | ||
| 15 | DHODH | 7152 | 658 | 4.437 | 0.7664 | Yes | ||
| 16 | CTPS | 2514 15772 | 662 | 4.414 | 0.7986 | Yes | ||
| 17 | PRPS1 | 24233 | 804 | 3.939 | 0.8199 | Yes | ||
| 18 | UMPS | 22606 1760 | 1746 | 1.888 | 0.7831 | No | ||
| 19 | RRM2 | 5401 5400 | 1791 | 1.841 | 0.7942 | No | ||
| 20 | IMPDH1 | 17197 1131 | 2099 | 1.444 | 0.7883 | No | ||
| 21 | PRPSAP1 | 20141 | 2183 | 1.331 | 0.7936 | No | ||
| 22 | AK3L1 | 8564 | 3394 | 0.355 | 0.7311 | No | ||
| 23 | AK5 | 6042 | 4304 | 0.172 | 0.6834 | No | ||
| 24 | KIF13B | 21982 21983 | 4731 | 0.130 | 0.6614 | No | ||
| 25 | NME7 | 926 4101 14070 3986 3946 931 | 5919 | 0.069 | 0.5981 | No | ||
| 26 | RRM2B | 6902 6903 11801 | 6260 | 0.059 | 0.5802 | No | ||
| 27 | AK1 | 4363 | 8516 | 0.018 | 0.4590 | No | ||
| 28 | PURA | 9670 | 10425 | -0.006 | 0.3564 | No | ||
| 29 | PRPSAP2 | 10013 1317 | 12947 | -0.053 | 0.2211 | No | ||
| 30 | CTPS2 | 12060 2571 | 16323 | -1.017 | 0.0470 | No | ||
| 31 | ADSSL1 | 21136 2087 | 17188 | -2.229 | 0.0168 | No | ||
| 32 | AK2 | 8563 2479 16073 | 17761 | -3.520 | 0.0118 | No | ||
| 33 | NME3 | 23349 | 18110 | -4.652 | 0.0272 | No |
